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How Do Tamoxifen and Femara Fight Breast Cancer
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Every year in the UK, around 16,000 people die from colorectal cancer, the second commonest cause of death from cancer in the UK after lung cancer.1 Over half of all people with colorectal cancer eventually die of metastatic disease.2 While median survival has increased with optimal use of combination chemoth More...
Each year in the UK, around 16,000 people die from colorectal cancer.1 At disease presentation, around 55% of people have advanced cancer that has spread to lymph nodes, metastasised to other organs or is so locally advanced that surgery is unlikely to be curative (Dukes\' stage C or D).2 Overall 5-year survi More...
Chronic swelling of the arm due to lymphoedema is a common complication of breast cancer treatment. As well as deformity, the condition can cause feelings of heaviness, tightness and aching in the arm. It can also lead to anxiety or depression, and difficulties with adjustment to the cancer and in family rela More...
Around 34,000 people in the UK die from lung cancer each year.1 Over 75% of patients with the disease have non-small-cell lung cancer ( ). Here, we discuss the role of chemotherapy in the management of NSCLC, a treatment that some medical oncologists estimate would benefit 50% of patients with NSCLC,2 but whi More...
Of the 30,000 people in the UK who develop colorectal cancer each year, around 70-80% undergo potentially curative surgery. Even so, around a half of all patients eventually die from metastatic disease, typically within 5 years of diagnosis. Many patients who develop metastases are offered systemic chemothera More...
The growth and multiplication of cells are regulated, in part, by polypeptide growth factors that bind to high-affinity receptors typically found on the plasma membrane. One such receptor is human epidermal growth factor receptor 2 (HER2). In around a quarter of all primary breast cancers, cells possess abnor More...
Each year in the UK, pancreatic cancer is diagnosed in around 7,000 people.1 At least 80% of these present with locally advanced inoperable or metastatic disease and most patients with pancreatic cancer die within a year of diagnosis. Here, we review treatment options, dealing exclusively with adenocarcinoma More...
